5/19/2011

How do hospitals deal with multi-drug resistant infections/diseases?

How do hospitals deal with multi-drug resistant infections/diseases?I was wondering, what are ALL of the ways to deal with infections that are resistant to antibiotics/anti viral medications/anti-fungal medications? How can you deal with such diseases? I know that you could use bacteriophages, and that "old-fashioned" medicines can work, but what are ALL of the other ways to deal with such diseases?

ohio_ob
I am a physician. There are very few bacteria that are resistant to all available antibiotics. There have been reports in Europe of Klebiella that is resistant to all antibiotics, and it is likely that this will occur in the USA. The way physicians deal with this is looking at the actual susceptibility data and finding what antibiotics a bacteria is least resistant to (most antibiotics that a bacteria is "resistant" to will stop or kill the bacteria in high enough concentration), then giving the patient as much of the drug as possible. There are also a couple antibiotics such as colisten and a few others that are considered too dangerous to use if there are any other options. Docs also have to be a little creative about where and how to deliver antibiotics - directly into the CSF, the bladder, or the abdominal cavity. There are some methods used by old-time docs like putting honey on wounds because it is bacteriostatic. Most docs follow these rules for infection treatment 1) remove the source - foley catheter, internal hardware, abscess, etc. 2) find and use appropriate antibiotics, and 3) prevent re-infection by limiting patient exposure to pathogens - hand washing, limit use of foleys, antibiotic prophylaxis, etc.

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